Lv4
730 积分 2023-08-07 加入
P-Glycoprotein Recognition of Substrates and Circumvention through Rational Drug Design
3天前
已完结
Design and Synthesis of E7820/Tasisulam Hybrids as Potential DCAF15 Binders
12天前
已完结
Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820
12天前
已完结
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
12天前
已完结
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
12天前
已完结
Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures
1个月前
已完结
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7(8H)-one derivatives as potent USP1 inhibitors
1个月前
已完结
Recent advances in anticancer mechanisms of molecular glue degraders: focus on RBM39-dgrading synthetic sulfonamide such as indisulam, E7820, tasisulam, and chloroquinoxaline sulfonamide
2个月前
已完结
Exploiting E3 ligases for lung cancer therapy: The promise of DCAF-PROTACs
2个月前
已完结
RBM39 silence suppresses esophageal cancer proliferation and metastasis via FANCD2 mRNA destabilization
6个月前
已完结
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