Lv7
4940 积分 2023-08-17 加入
Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ
5小时前
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Potent Uncompetitive Inhibitors of Nicotinamide N-Methyltransferase (NNMT) as In Vivo Chemical Probes
5小时前
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Enhancing nicotinamide N-methyltransferase bisubstrate inhibitor activity through 7-deazaadenosine and linker modifications
5小时前
已完结
High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT)
5小时前
已完结
Mechanisms and inhibitors of nicotinamide N-methyltransferase
5小时前
已完结
Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
5小时前
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Design, Biological Characterization, and Discovery of Novel Cyclohexenyl Derivatives as Kinesin KIF18A Inhibitors for the Treatment of Ovarian Cancer
1个月前
已完结
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe
1个月前
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Pharmacophore-oriented 3D molecular generation toward efficient feature-customized drug discovery
1个月前
已完结
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders
1个月前
已完结
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