Lv7
4990 积分 2023-08-17 加入
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
2天前
已完结
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
13天前
已完结
Recent advances from computer-aided drug design to artificial intelligence drug design
1个月前
已完结
Evolution of Molecular Generation Models in Drug Discovery
1个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
1个月前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
1个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
1个月前
已完结
A single inhibitor for all KRAS mutations
1个月前
已完结
Deep Lead Optimization: Leveraging Generative AI for Structural Modification
1个月前
已完结
Deep contrastive learning enables genome-wide virtual screening
2个月前
已完结
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