Lv51
1040 积分 2024-03-27 加入
Self-Dimerization Induced Proximity Targeting Chimeras (SDIPTAC) Lead to DCAF1 Loss of Function and Inhibition of HIV Replication
11天前
已完结
Rewiring cancer drivers to activate apoptosis
13天前
已完结
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
15天前
已完结
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity
19天前
已完结
Design and evaluation of selective BET PROTACs with potent antitumor efficacy and safety against acute myeloid leukemia
19天前
已完结
Structural optimization of AR and AR-V7 degraders incorporating silicon-based hydrophobic tags for treatment of castration-resistant prostate cancer
20天前
已完结
Structure-Based Discovery and Optimization of Furo[3,2- c]pyridin-4(5 H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors
20天前
已完结
Promoting Secretion of Pathological Tau Species Using an Induced Proximity Platform That Engages the Autophagy Pathway
21天前
已完结
Self-Dimerization Induced Proximity Targeting Chimeras (SDIPTAC) Lead to DCAF1 Loss of Function and Inhibition of HIV Replication
21天前
已完结
Methods to Study the Molecular Mechanism and Drive the Design of Protein Degraders
22天前
已完结
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