Lv51
890 积分 2025-10-14 加入
Abstract C086: First-in-class PI3Kα-targeting degrader antibody conjugates (DACs) for selective and safer treatment of PI3Kα-driven cancers
4小时前
待确认
POS0442 GLPG4399: SELECTIVE SIK3 INHIBITION AS A NOVEL MODE OF ACTION FOR THE TREATMENT OF INFLAMMATORY ARTHRITIC DISEASES (PRECLINICAL)
28天前
已完结
Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer
1个月前
已完结
Derivation of AZD5335, a novel FRα-targeted TOP1i-loaded ADC, for the treatment of FRα-expressing cancers
1个月前
已完结
Nanobody-Engineered Bispecific IL-18 Mimetics Drive Antitumor Immunity by Engaging CD8+ T Cells and Evading IL-18BP in Preclinical Models
1个月前
已完结
Discovery of Covalent and Cell‐Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo
1个月前
已完结
Extracellular Vesicles from Adipose-Derived Stem Cells Promote Diabetic Wound Healing via the PI3K-AKT-mTOR-HIF-1α Signaling Pathway
1个月前
已完结
Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy
1个月前
已完结