Lv5
1320 积分 2025-09-23 加入
Efficacy and safety of tocilizumab therapy in patients with systemic juvenile idiopathic arthritis. Results of a retrospective cohort study
3天前
求助中
Population Pharmacokinetic–Pharmacodynamic Model of Serum Transthyretin Following Patisiran Administration
10天前
已完结
Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure‐Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin‐Mediated (hATTR) Amyloidosis
10天前
已关闭
Pharmacokinetics and Pharmacodynamics of Patisiran in Patients with hATTR Amyloidosis and with Polyneuropathy After Liver Transplantation
10天前
已关闭
Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides
11天前
已完结
Phase 1 study of ALN-TTRsc02, a subcutaneously administered investigational RNAi therapeutic for the treatment of transthyretin-mediated amyloidosis
11天前
已完结
Pharmacokinetics and Pharmacodynamics of Patisiran in Patients with hATTR Amyloidosis and with Polyneuropathy After Liver Transplantation
16天前
已完结
SGLT2 Inhibitors in Patients with Heart Failure: A Model-Based Meta-Analysis
17天前
已完结
Mechanistic Pharmacokinetics and Pharmacodynamics of GalNAc-siRNA: Translational Model Involving Competitive Receptor-Mediated Disposition and RISC-Dependent Gene Silencing Applied to Givosiran
26天前
已完结
Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans
1个月前
已完结
Current Standard and Future Perspectives in Non-Surgical Therapy for Hepatocellular Carcinoma
4个月前
已采纳
Poor ovarian response: the fertility ultramarathon and the decision to go one more
5个月前
已采纳
Arthroscopic Debridement of Mild and Moderate Knee Osteoarthritis Results in Clinical Improvement at Short-Term Follow-Up: A Systematic Review
5个月前
已采纳