Lv3
308 积分 2022-07-12 加入
Photostability of Topoisomerase I Inhibitor Conjugated IgG1 Antibody–Drug Conjugates: Characterization Study and Degradation Mechanism Analysis
6天前
已完结
Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis
10天前
已完结
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors
21天前
已完结
Evaluation of Double Self-Immolative Linker-Based Antibody–Drug Conjugate FDA022-BB05 with Enhanced Therapeutic Potential
1个月前
已完结
Cathepsin B-Responsive Phosphatidylinositol 3-Kinase (PI3K) Prodrug for the Treatment of Pulmonary Fibrosis
1个月前
已完结
FZ-AD005, a Novel DLL3-Targeted Antibody–Drug Conjugate with Topoisomerase I Inhibitor, Shows Potent Antitumor Activity in Preclinical Models
1个月前
已完结
Radiation-Activated Resiquimod Prodrug Nanomaterials for Enhancing Immune Checkpoint Inhibitor Therapy
1个月前
已完结
Azide‐Masked Resiquimod Activated by Hypoxia for Selective Tumor Therapy
1个月前
已完结
Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates
1个月前
已完结
Cleavable linkers in antibody–drug conjugates
1个月前
已完结
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