Lv3
238 积分 2022-07-12 加入
Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class
14小时前
待确认
Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads
15小时前
已完结
Clinical Pharmacology and Translational Science Considerations in the Development of Dual‐Payload Antibody Drug Conjugates
1天前
已完结
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors
1天前
已完结
Molecule engineering strategy of toll-like receptor 7/8 agonists designed for potentiating immune stimuli activation
1天前
已完结
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
2天前
已完结
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
2天前
已完结
Photostability of Topoisomerase I Inhibitor Conjugated IgG1 Antibody–Drug Conjugates: Characterization Study and Degradation Mechanism Analysis
10天前
已完结
Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis
14天前
已完结
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors
25天前
已完结
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