Lv2
104 积分 2022-01-24 加入
Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity
1天前
已完结
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2)
3天前
已完结
Development of Degraders of Cyclin-Dependent Kinases 4 and 6 Based on Rational Drug Design
11天前
已完结
Design, synthesis, and antitumor activity of benzimidazole derivatives as CDK4/6 inhibitors
14天前
已完结
JHD205, A Novel Abemaciclib Derivative, Exerts Antitumor Effects on Breast Cancer by CDK4/6
14天前
已完结
Design and Synthesis of New bis-oxindole and Spiro(triazole-oxindole) as CDK4 Inhibitors with Potent Anti-breast Cancer Activity
14天前
已完结
Design, synthesis and profiling of proteolysis-targeting chimeras (PROTACs) as CDK4/6 degraders
16天前
已完结
Design, synthesis and anti-bladder cancer activity of novel dihydroartemisinin-ibuprofen hybrids
18天前
已完结
Structure-based design of potent pyrazolo[1,5- a ]pyrimidine CDK4/6 inhibitors: biological evaluation and computational validation
18天前
已完结
Novel β-carboline quaternary ammonium salts: design, synthesis, structural insight and antitumor activity
18天前
已完结