Lv71
4990 积分 2022-12-22 加入
The synthetic landscape of cereblon (CRBN) binders: from thalidomide to emerging chemotypes
3小时前
待确认
Synthesis, Characterization, Antimicrobial Activity, and Docking Studies of New Triazolic Tripodal Ligands
9小时前
待确认
Sulfonate Derivative of HOAt (CTSOAt) as a Coupling Reagent for the Construction of C–N, C–O, and C–C Bonds
14天前
已完结
New Drugs Approved by the FDA in 2025: Synthesis and Clinical Applications
14天前
已完结
A Rationally Designed Novel Bifunctional Human TNF-α- and Janus Kinase-Targeted soloMER Drug Conjugate (SDC) with a Neutrophil Elastase Cleavable Linker Delivering Inflammation Site-Specific Release of Payload
18天前
已完结
Discovery of Tivumecirnon (FLX475), a Potent and Selective CCR4 Antagonist That Inhibits the Migration of Immunosuppressive Regulatory T Cells into the Tumor Microenvironment to Restore Antitumor Immunity
18天前
已完结
Discovery of BBI-355, a Potent, Selective, and Orally Available Checkpoint Kinase 1 Inhibitor for the Treatment of Extrachromosomal DNA Oncogene-Amplified Cancers
18天前
已完结
Antitumour imidazotetrazines. Part 39. Synthesis of bis(imidazotetrazine)s with saturated spacer groups
19天前
已完结
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
24天前
已完结
PASE synthesis of 1-azolyl-1H-1,2,4-triazoles by the reaction of diazoazoles with ethyl isocyanoacetate
27天前
已完结
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