Lv71
4980 积分 2022-12-22 加入
Single-Stranded siRNAs Activate RNAi in Animals
3小时前
待确认
Discovery of long-acting APOC3 siRNA for treating patients with hypertriglyceridemia
1天前
待确认
Development of a Scalable Method for Manufacturing the Central Core of CD73 Inhibitor AB680
1天前
待确认
Unlocking the potential of RNAi as a therapeutic strategy against infectious viruses: an in-silico study
4天前
已完结
Physicochemical and Biological Evaluation of gem ‐Difluorinated Saturated Oxygen Heterocycles as Bioisosteres for Drug Discovery
11天前
已完结
Discovery of 3-trifluoromethyl-substituted pyrazoles as selective phosphodiesterase 10A inhibitors for orally attenuating isoprenaline-induced cardiac hypertrophy
17天前
已完结
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
18天前
已完结
Mechanistic Evidence for Mild Base-Mediated Intermolecular Trans-Aminoacylations of 1-Acyl-5-amino-1H-1,2,4-triazoles and 5-Amino-1H-1,2,4-triazoles to Afford 5-Acylamino-1H-1,2,4-triazoles
22天前
已完结
RNAi-based drug design: considerations and future directions
25天前
已完结
Spirocyclopentane as a Novel Scaffold for Potent Ghrelin Receptor Full Agonists
1个月前
已完结