Lv1
50 积分 2026-01-01 加入
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment
2个月前
已完结
Cyclin-dependent kinase 4 and 6 inhibitors in breast cancer treatment
2个月前
已完结
Cyclin-dependent kinase 4/6 Inhibitor Abemaciclib and Histone deacetylase Inhibitor Panobinostat Treatment Exerts Metabolic Reprogramming of Pancreatic Cancer Cells
2个月前
已关闭
Design and synthesis of novel cyclin-dependent kinase 4/6(CDK4/6) and histone deacetylase (HDAC) dual inhibitors: In vitro and in vivo anticancer activity
2个月前
已完结
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
2个月前
已完结
Preclinical validation of a novel brain-penetrant PET ligand for visualization of histone deacetylase 6: a potential imaging target for neurodegenerative diseases
2个月前
已完结
Preclinical and Clinical Studies of Chidamide (CS055/HBI-8000), An Orally Available Subtype-selective HDAC Inhibitor for Cancer Therapy
3个月前
已完结
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