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60 积分 2025-02-05 加入
Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition
7天前
已完结
Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-xL, display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity
12天前
已完结
TJ0113 attenuates fibrosis in metabolic dysfunction-associated steatohepatitis by inducing mitophagy
28天前
已完结
Celastrol Targets Hsc70‐Bim Interaction as a Novel Senolytic to Extend Lifespan and Mitigate Organ Fibrosis
28天前
已完结
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
29天前
已完结
Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration
1个月前
已完结
Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 1
2个月前
已完结
Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition
2个月前
已完结
Discovery of novel salidroside derivatives as potent hypoxia inducible factor 1α (HIF-1α) signaling inhibitors to treat high altitude cerebral edema
2个月前
已完结
Biomarkers of cellular senescence in idiopathic pulmonary fibrosis
3个月前
已完结
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