Lv11
8 积分 2026-01-06 加入
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9
7小时前
已完结
Targeting the Non-Catalytic Functions: a New Paradigm for Kinase Drug Discovery?
8小时前
已完结
FDA approves 100th small-molecule kinase inhibitor
10小时前
已完结
Discovery of a Potent, Selective and In Vivo Active Aurora A PROTAC Degrader from a Promiscuous Kinase Inhibitor
2天前
已完结
Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor
4个月前
已完结
Design, Optimization and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties
4个月前
已完结
Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras
4个月前
已完结
CRISPR Screen Reveals BRD2/4 Molecular Glue-like Degrader via Recruitment of DCAF16
4个月前
已完结
CRISPR Screen Reveals BRD2/4 Molecular Glue-like Degrader via Recruitment of DCAF16
4个月前
已完结
Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders
4个月前
已完结
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