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28 积分 2026-01-06 加入
Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines?
1天前
已完结
Importin α phosphorylation promotes TPX2 activation by GM130 to control astral microtubules and spindle orientation
5天前
已完结
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2
5天前
已关闭
Discovery of a Highly Subtype-Selective AURKA PROTAC Degrader (CT3) with Superior Activity to the Inhibitor for Hematological Malignancies
6天前
已完结
Targeting KRAS in cancer
7天前
已完结
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
7天前
已完结
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A
8天前
已完结
Small-Molecule Hydrophobic Tagging: A Promising Strategy of Druglike Technology for Targeted Protein Degradation
8天前
已完结
Discovery ofHighly Efficacious CRBN-Based KRAS DegradersTargeting Cancers with KRAS G12D and G12V Mutations
8天前
已完结
Photocatalytic fluoroalkyl radical-initiated construction of fluorinated heterocycles: mechanisms and applications
13天前
已完结
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