Lv43
526 积分 2024-08-19 加入
Discovery of SZJK-0421: A Novel Potent, Low Toxicity, Selective Second Generation of CRM1 Inhibitor for the Treatment of Both Hematological and Solid Tumors
3小时前
待确认
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
4小时前
已完结
Discovery of 5-Nitro-N-(3-(trifluoromethyl)phenyl) Pyridin-2-amine as a Novel Pure Androgen Receptor Antagonist against Antiandrogen Resistance
4小时前
已完结
Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression
2天前
已完结
Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma
5天前
已完结
Non-canonical functions of UGT2B17 promote castrate-resistant prostate cancer progression
5天前
已完结
Targeting mTORC2-Dependent AKT/FOXO1/RNF125 signaling exploits a therapeutic vulnerability in c-MET-activated and β-catenin-mutated hepatocellular carcinoma
5天前
已关闭
USP22 drives tumor immune evasion and checkpoint blockade resistance through EZH2-mediated epigenetic silencing of MHC-I
14天前
已完结
SIGLEC12 mediates plasma membrane rupture during necroptotic cell death
14天前
已完结
Eradicating Drug-tolerant Persister Cells in EGFR- Mutated Non–Small Cell Lung Cancer by Targeting TROP2 with CAR-T Cellular Therapy
28天前
已完结