Lv3
250 积分 2025-09-02 加入
Pharmacokinetic Studies of a Novel c-Met Targeting PROTAC Drug Candidate Using UPLC-MS/MS Quantification Methods
11天前
已完结
Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment
1个月前
已完结
Discovery of potent CRBN-recruiting epidermal growth factor receptor (EGFR) degraders in vitro
1个月前
已完结
Development of Dual-Receptor Lysosome-Targeting Chimeras for Protein Degradation
1个月前
已完结
Dual-PROTACs based on natural product derivative potassium dehydrographolide succinate: design, synthesis, and antitumor activity of a novel EGFR degrader
1个月前
已完结
Preclinical characterization of TGRX-678, a brain-penetrant allosteric inhibitor of BCR::ABL1
4个月前
已完结
BRAF oncogenic mutants evade autoinhibition through a common mechanism
4个月前
已完结
Novel Highly Potent c-Met Degraders against a Broad Range of Cancers
6个月前
已完结
Rational Design, Synthesis, and Biological Evaluation of Novel c-Met Degraders for Lung Cancer Therapy
6个月前
已完结
A Cyclized Bivalent Aptamer-Based Protein Degrader Targeting Receptor Tyrosine Kinases Overcomes Resistance to Inhibitors in Lung Cancer
6个月前
已完结
The Molecular Basis of Pancreatic Fibrosis Common Stromal Gene Expression in Chronic Pancreatitis and Pancreatic Adenocarcinoma
7个月前
已撤回
Amendments to the Perceived Restorative Components Scale for Children (PRCS-C II)
7个月前
已采纳
Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy
7个月前
已采纳