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16 积分 2025-07-15 加入
LX1 Dual Targets AR Variants and AKR1C3 in Advanced Prostate Cancer Therapy
14天前
已完结
Discovery of Highly Selective AKR1C3 Inhibitors to Overcome EGFR C797S-Mediated Osimertinib Resistance in Non-Small Cell Lung Cancer
19天前
已完结
Abstract 5760: Metabolic rewiring renders KEAP1 -mutant lung cancers sensitive to AKR1C3-activated prodrugs
1个月前
已关闭
Emerging small-molecule AKR1C3 inhibitors development for cancer therapy: Progress from 2021 to 2025
1个月前
已完结
KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer
2个月前
已完结
ACSL5 regulated acetyl-CoA to promote bladder cancer cellular senescence via 53BP1 acetylation
2个月前
已完结
Casticin activates Rheb GTPase by binding to residue Trp141 and induces tumor senescence
3个月前
已完结
Senescent cells in cancer therapy: why and how to remove them
3个月前
已完结
Therapy-induced senescence — an induced synthetic lethality in liver cancer?
3个月前
已完结
A senescence-responsive nanodrug amplifies radiotherapy efficacy
3个月前
已完结