Lv52
908 积分 2025-06-24 加入
Melatonin protects against myocardial ischemia-reperfusion injury by inhibiting excessive mitophagy through the Apelin/SIRT3 signaling axis
6小时前
已完结
ERRα transcriptionally activates METRNL, ameliorating cardiomyocyte apoptosis and inflammatory injury in septic cardiomyopathy through the NF-κB/NLRP3 pathway
1天前
已完结
A Multifunctional Hydrogel Integrating Hemostatic, Antioxidant, and Antibacterial Properties for Infected and Diabetic Wound Regeneration
13天前
已完结
ClpP Activation in High-Risk Medulloblastoma: ONC206 as a Potent Inducer of the Integrated Stress Response and Mitochondrial Damage for a Broader Therapeutic Window
13天前
已完结
Targeting caseinolytic mitochondrial matrix peptidase, a novel contributor to the pathobiology of high-risk multiple myeloma
13天前
已完结
Decreased LONP1 expression exacerbates MASH-induced liver fibrosis via elevated orotic acid levels
15天前
已完结
The mitochondrial protease ClpP is a metabolic vulnerability and an immunogenic trigger against multiple myeloma
15天前
已完结
Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression
15天前
已完结
Lonp1 inhibition disrupts mitochondrial function in the hippocampus and drives an aging-like synaptic and cognitive phenotype in adult SAMP8 mice
15天前
已完结
Inhibiting VDAC1 oligomerization attenuated cerebral ischemia-reperfusion injury by promoting mitophagy via reduced LONP1 interaction
15天前
已完结