Lv2
128 积分 2025-02-27 加入
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA
13天前
已完结
Synthetic routes and clinical application of Small-Molecule HER2 inhibitors for cancer therapy
13天前
已完结
Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein–Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases
1个月前
已完结
Thiazole‐based IL‐17 inhibitors discovered by scaffold morphing
1个月前
已完结
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors
1个月前
已完结
Small molecule interleukin 17A/A antagonists and antibodies blocking both IL17A/A & IL17A/F demonstrate equivalent degrees of efficacy in preclinical models of skin and joint inflammation
1个月前
已完结
Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators
1个月前
已完结
Turning Off STAT6 with a Targeted Degrader
1个月前
已完结
Spirohypertones A and B as potent antipsoriatics: Tumor necrosis factor-α inhibitors with unprecedented chemical architectures
1个月前
已完结
An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
1个月前
已完结
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