Lv31
348 积分 2025-04-23 加入
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
3小时前
已完结
Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction
3小时前
已完结
Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction
3小时前
已完结
Ordering of the N-Terminus of Human MDM2 by Small Molecule Inhibitors
3小时前
已完结
Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development
3小时前
已完结
Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors
3小时前
已完结
Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction
3小时前
已完结
Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres
3小时前
已完结
Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction
3小时前
已完结
Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development
3小时前
已完结
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