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172 积分 2025-03-18 加入
Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5
21天前
已完结
Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders
1个月前
已完结
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
1个月前
已完结
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
1个月前
已完结
A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition
1个月前
已完结
Targeting both wild-type EGFR and its drug-resistant mutants with erlotinib-aptamer conjugates
2个月前
已完结
LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity
2个月前
已完结
Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5
3个月前
已完结
Crystal structure of the human PRMT5:MEP50 complex
3个月前
已完结
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor
3个月前
已完结
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