Lv1
100 积分 2024-10-12 加入
An orally available non-nucleotide STING agonist with antitumor activity
18小时前
待确认
TL1A blockade in inflammatory bowel diseases: Clinical trials to watch
1个月前
已完结
Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders
1个月前
已完结
Microglial STING activation promotes neuroinflammation and pathological changes in experimental mice with intracerebral haemorrhage
1个月前
已完结
Method to quantify cytokines and chemokines in mouse brain tissue using Bio-Plex multiplex immunoassays
2个月前
已完结
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis
3个月前
已完结
Blockade of IL-1α and IL-1β signaling by the anti-IL1RAP antibody nadunolimab (CAN04) mediates synergistic anti-tumor efficacy with chemotherapy
4个月前
已完结
First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours
4个月前
已完结
Discovery and development of SIM0709, a novel bi-specific antibody targeting TL1A and IL23p19 for the treatment of IBD and beyond 4676
4个月前
已完结
Is Target-Based Drug Discovery Efficient? Discovery and “Off-Target” Mechanisms of All Drugs
5个月前
已完结
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