Lv2
136 积分 2024-10-13 加入
Novel O-methylpyrimidine prodrugs of phenolic compounds bioactivated by aldehyde oxidase: Enhancing metabolic stability against first-pass conjugative metabolism in the intestine
3天前
已完结
Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase
3天前
求助中
Structure and properties of an oxidative metabolite of 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide generated by aldehyde oxidase
3天前
已关闭
In Vitro Metabolism of 2-Methoxy-N-[3-[4-[3-methyl-4-[(6-methyl- 3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide (CP-724,714) by Aldehyde Oxidase and Predicting Its Percent Contribution Relative to CYP-Mediated Metabolism
3天前
已关闭
In Vitro Microsomal Hepatic Metabolism of Antiasthmatic Prototype LASSBio-448
4天前
已关闭
Cytochrome P450 2B6 and UDP-Glucuronosyltransferase Enzyme–Mediated Clearance of Ciprofol (HSK3486) in Humans: The Role of Hepatic and Extrahepatic Metabolism
9天前
已完结
Context-informed subgraph foundation models enable interpretable protein-function prediction
16天前
已完结
Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
21天前
已关闭
Drug and pro-drug substrates and pseudo-substrates of human butyrylcholinesterase
30天前
已完结
Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug
1个月前
已完结
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