Lv1
40 积分 2024-09-24 加入
Safety considerations for cereblon-recruiting targeted protein degraders
3天前
已完结
New Reversible Covalent Warheads: Cyanobenzothiazoles Recruiting DCAF16 for Targeted Protein Degradation
4天前
已完结
Benzothiophene-based, orally active PIK3CA H1047R mutant-selective inhibitors for the treatment of HR+/HER2- breast cancer
7天前
已完结
Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers
14天前
已完结
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor
14天前
已完结
ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation
15天前
已完结
Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation
22天前
已完结
Identification of ACK1 inhibitors as anticancer agents by using computer-aided drug designing
22天前
已完结
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry
27天前
已完结
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting
1个月前
已完结
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