Lv21
120 积分 2024-09-24 加入
Discovery of Bifunctional Oncogenic Target Inhibitors against Allosteric Mitogen-Activated Protein Kinase (MEK1) and Phosphatidylinositol 3-Kinase (PI3K)
4小时前
待确认
A New Era of Artificial Intelligence (AI): Transforming Drug Discovery and Development
5天前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
5天前
已完结
Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy
5天前
已完结
Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)
5天前
已完结
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
6天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
19天前
已完结
Targeted protein degradation: expanding the toolbox
19天前
已完结
Molecular glues for protein-protein interactions: Progressing toward a new dream
19天前
已完结
DEVELOPMENT OF E3 LIGANDS TO ENABLE NEXT-GENERATION DEGRADERS
27天前
已完结
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