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100 积分 2024-09-24 加入
Design, Synthesis, and Evaluation of Nucleolin-Bridged, MDM2-Recruiting IRAK4 Degraders for the Treatment of Autoimmune Diseases
23小时前
待确认
Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)
12天前
已完结
Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation
14天前
已完结
Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability
15天前
已完结
Discovery of Bifunctional Oncogenic Target Inhibitors against Allosteric Mitogen-Activated Protein Kinase (MEK1) and Phosphatidylinositol 3-Kinase (PI3K)
16天前
已完结
A New Era of Artificial Intelligence (AI): Transforming Drug Discovery and Development
21天前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
21天前
已完结
Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy
21天前
已完结
Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)
22天前
已完结
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
22天前
已完结
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