Lv1
40 积分 2020-12-06 加入
Discovery ofDeuterated 3,4-Dihydro-benzo[ e ][1,4]diazepine-2,5-dioneDerivatives as Potent, Selectiveand Orally Bioavailable ROCK2 Inhibitors
3天前
已完结
Generative AI-Assisted Discovery of HPK1 Inhibitors
9天前
已完结
A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death
1个月前
已完结
Discovery of Potential First-in-Class Dual Ligand-Directed Degrader and Antagonist of the Androgen Receptor: BMS-986365
1个月前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
1个月前
已完结
Selective CDK2 Degradation via Noncanonical Recruitment
2个月前
已完结
Discovery of SMD-6346: A Potent, Selective, and Orally Active SMARCA2 Degrader for Targeting SMARCA4-Deficient Human Cancers
2个月前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
3个月前
已完结
Discovery of BRD4–HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans
4个月前
已完结
Robust Synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate: A Key Intermediate in the Preparation of an HIV NNRTI Candidate
5个月前
已完结
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