Lv11
30 积分 2020-12-06 加入
Conserved class B GPCR activation by a biased intracellular agonist
1小时前
待确认
Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist
1小时前
已完结
NAVIGATING CHALLENGES IN ORAL HETEROBIFUNCTIONAL DEGRADERS: INSIGHTS AND STRATEGIES FOR EARLY-STAGE PROJECTS
15天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
22天前
已完结
Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective
1个月前
已完结
Discovery of CFT8634, a Potent, Selective, and Orally Bioavailable Heterobifunctional Degrader of BRD9
1个月前
已完结
Development of chiral praziquantel analogues as potential drug candidates with activity to juvenile Schistosoma japonicum
1个月前
已完结
Rare Case of Polymorphism in the Binary System of Enantiomers of a Praziquantel Derivative
1个月前
已完结
Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists
1个月前
已完结
Discovery of BRD4–HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans
1个月前
已完结