Lv4
732 积分 2024-11-15 加入
Different in vitro and in vivo tools for elucidating the human metabolism of alpha‐cathinone‐derived drugs of abuse
16小时前
已完结
Computational Insights into the Regioselective Hydroxylation of Nirmatrelvir Metabolized by Cytochrome P450 3A4
16小时前
已完结
Viral target and metabolism‐based rationale for combined use of recently authorized small molecule COVID‐19 medicines: Molnupiravir, nirmatrelvir, and remdesivir
16小时前
待确认
Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity
7天前
已关闭
Novel DAG‐Lactone‐Based Vav1 Inhibitors Show Anti‐proliferative Activity in Pancreatic Cancer Models
10天前
已完结
Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement
25天前
已完结
Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome
25天前
已完结
Deep-Learning-Driven Discovery of SN3–1, a Potent NLRP3 Inhibitor with Therapeutic Potential for Inflammatory Diseases
25天前
已完结
Discovery of Novel NLRP3 Inflammasome Inhibitors Composed of an Oxazole Scaffold Bearing an Acylsulfamide
25天前
已完结
Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition
25天前
已完结
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