Lv1
50 积分 2024-12-03 加入
Intercepting the Downstream of the Estrogen Receptor Signaling Pathway: Discovery of a Potent and Efficient SRC-3 PROTAC Degrader for Overcoming Endocrine Resistance Breast Cancer
12天前
已完结
Chemical Space Navigation of Nitidine Leads to the Discovery of a Novel PD-L1 Degradation Agent by Targeting CSN5 for Enhanced Antitumor Immunity
1个月前
已完结
Celastrol Elicits Antitumor Effects through Inducing Immunogenic Cell Deathand Downregulating PD-L1 in ccRCC
3个月前
已完结
Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer
4个月前
已完结
Anti-inflammation Mechanisms of Flavones Are Highly Sensitive to the Position Isomers of Flavonoids: Acacetin vs Biochanin A
4个月前
已完结
Reducing PD-L1 Expression by Degraders and Downregulators as a Novel Strategy to Target the PD-1/PD-L1 Pathway
5个月前
已完结
Metformin Enhances PD ‐ L1 Inhibitor Efficacy in Ovarian Cancer by Modulating the Immune Microenvironment and RBMS3 Expression
5个月前
已完结
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models
5个月前
已完结
The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma
6个月前
已完结
Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer
8个月前
已完结
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