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118 积分 2026-02-07 加入
Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance
1个月前
已完结
DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment
1个月前
已完结
Design of Potent Menin–KMT2A Interaction Inhibitors with Improved In Vitro ADME Properties and Reduced hERG Affinity
1个月前
已完结
Application of Model‐Informed Drug Development in Dose Selection and Optimization for siRNA Therapies
2个月前
已完结
Inhibition of UDP-glucuronosyltransferases by fedratinib, implying a high risk of drug-drug interactions
3个月前
已完结
UDP-Glucuronosyl transferase mediated drug-drug interactions: An Industry perspective on recommended in vitro studies
3个月前
已完结
Ketone Reduction Drives Major Circulating Metabolites of GDC-8264 in Humans
5个月前
已关闭
Metabolite Profiling and Identification of Semaglutide in Liver S9 Across Species and Rat Plasma
5个月前
已完结
Assessing DDI risks in drug discovery and development: approaches, challenges, and trends
7个月前
已完结
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