Lv1
90 积分 2023-03-24 加入
Discovery of 1-(Azetidin-3-ylmethyl)-1H-benzo[d]imidazole Derivatives as Efficient GSTP1 Inhibitors for Gastric Cancer Treatment via Warhead Removal Strategy
9天前
已完结
Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia
2个月前
已完结
Design and Evaluation of a Folate-Targeted PEG-MMAE Conjugate with Enzyme-Activated Drug Release for Enhanced Tumor Selectivity and Antitumor Efficacy
2个月前
已完结
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
3个月前
已完结
Unveiling conformation-selective regulation of the norepinephrine transporter
4个月前
已完结
Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist (S)-STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis
4个月前
已完结
Structural insights into the activation of TMEM175 by small molecule
4个月前
已完结
Discovery of Imidazo[1,2-a]pyrazine Derivatives as Potent ENPP1 Inhibitors
5个月前
已完结
Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity
6个月前
已完结
Discovery of potent free fatty acid receptor 1 full agonists with a novel scaffold bearing conjugated double bond linker
7个月前
已完结