Lv51
956 积分 2022-10-31 加入
Identification of a novel aβ-overlapping binding site on the TREM2 Ectodomain engaged by the small-molecule agonist VG-3927
9天前
已完结
Discovery and Characterization of RP04340: A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
10天前
已完结
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas
22天前
已完结
Novel Dual Soft Drug Strategy Enables Development of Topical Androgen Receptor Antagonists with Enhanced Efficacy and Optimized Safety for Androgenetic Alopecia
1个月前
已完结
Inhibition of Kornblum Reaction with Lithium Salts in SN2 Reactions of Sulfonates and a Nucleophile Containing a Pyridine N-Oxide Moiety: Convergent and Selective Synthesis of an MRGPRX2 Antagonist
1个月前
已完结
Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases
1个月前
已完结
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent Cancers
2个月前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
2个月前
已完结
皖公网安备34019202002308
