Lv5
936 积分 2022-10-31 加入
Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases
4天前
已完结
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent Cancers
12天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
29天前
已完结
Routes to molecular glue degrader discovery
29天前
已完结
Sulfonic Acid Promoted N-Boc-, N-Cbz-, and N-PMB Cleavage in 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) and Application to Acid Sensitive Substrates
1个月前
已完结
Early Process Development of a Heterobifunctional Protein Degrader
2个月前
已完结
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
2个月前
已完结
Copper–Nitroxyl-Catalyzed α-Oxygenation of Cyclic Secondary Amines Including Application to Late-Stage Functionalization
2个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
2个月前
已完结
https://www.nature.com/articles/s44160-025-00915-3?utm_source=xmol&utm_medium=affiliate&utm_content=meta&utm_campaign=DDCN_1_GL01_metadata
5个月前
已关闭
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