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16 积分 2022-02-17 加入
ADME investigations of novel therapeutic modalities: challenges and opportunities 2025
16天前
已完结
Design, Synthesis, and Biological Evaluation of Pyrrolo[2,3-c]pyridin-7-one Derivatives as PKMYT1 Inhibitors Targeting CCNE1-Amplified Cancers
1个月前
已完结
A universal immunocapture LC−MS/MS method for humanized IgG1−based drugs in cynomolgus monkeys
1个月前
已完结
Recent advances in the discovery of PKMYT1-targeting drugs: a patent review (2021–2025)
3个月前
已完结
The importance of plasma protein and tissue binding in a drug discovery program to successfully deliver a preclinical candidate
3个月前
已完结
Discovery of Tetracyclic Derivatives as Highly Potent, Selective, and Bioavailable PKMYT1 Inhibitors for Cancer Therapy
3个月前
已完结
Re-Evaluating Antibody–Drug Conjugate Linker Stability: Assessment, Interpretation, and Clinical Translation
3个月前
已完结
Systematic Evaluation of Maleimide Spacer Impact on Drug-Linker Deconjugation in Antibody-Drug Conjugates Ex Vivo and In Vivo
4个月前
已完结
Excretion of Drugs and Their Metabolites into the Bile
5个月前
已完结
Perspectives on the use of machine learning for ADME prediction at AstraZeneca
5个月前
已完结
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