Lv41
510 积分 2025-09-05 加入
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
30分钟前
求助中
Evolving CRBN ligands enhance the drug-like properties of protein degraders
2天前
已完结
Skeletal editing of tetrahydrofurans to pyrrolidines through O-to-N single atom swap
6天前
已完结
An alkyl-swap platform for late-stage modification of secondary N-methylamines
6天前
已完结
Stereoretentive decarbonylative C(sp3)-C(sp3) cross-coupling
6天前
已完结
Access to N2-Substituted (Aza)Indazoles
7天前
已完结
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
7天前
已完结
Identification of XZ8078 as a Dual-Target Degrader Targeting PARP1 and IKZF3 for Broad Spectrum Anticancer Treatment
7天前
已完结
An Update on Clinically Advanced PROTAC Degraders and Their Synthesis
9天前
已完结
Nature-Inspired Continuous N-C Chain Elongation Enables Sustainable Peptide Synthesis
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