Lv44
480 积分 2025-09-05 加入
Drug Discovery with Privileged Building Blocks
31分钟前
待确认
Design, synthesis and biological evaluation of novel 3,4-dihydro-2H-[1,4]oxazino [2,3-f]quinazolin derivatives as EGFR-TKIs
1天前
待确认
Late-stage functionalization with strain-release warheads enables tunable covalent inhibition
2天前
已完结
Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics
7天前
已完结
Optimization of a Second-Generation, Highly Selective Polθ/PARP1 Dual Inhibitor with Improved Pharmacokinetics and Potent Activity against HR-Deficient Tumors
10天前
已完结
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy
15天前
已完结
Oxetane-to-azetidine skeletal editing
18天前
已完结
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
18天前
已完结
Safety, Tolerability, and Pharmacokinetics of Mufemilast, a PDE4 Inhibitor, in Healthy Participants: A First-in-Human Phase 1 Study
21天前
已完结
Discovery of a Potent, Selective, and Orally Bioavailable Achiral MAT2A Inhibitor for Treating MTAP-Deficient Cancers
24天前
已完结
Nature-Inspired Continuous N-C Chain Elongation Enables Sustainable Peptide Synthesis
皖公网安备34019202002308
