Lv11
40 积分 2023-07-13 加入
Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4
4小时前
待确认
Trichloromethyl Carbanion in Aqueous Micelles: Mechanistic Insights and Access to Carboxylic Acids from (Hetero)aryl Halides
17天前
已完结
The Synthesis of 4‐Hydroxypipecolic Acids by Stereoselective Cycloaddition of Configurationally Stable Nitrones
18天前
已完结
Preparation of (2S,4R)-4-Hydroxypipecolic Acid and Derivatives
18天前
已完结
Synthesis of N-Substituted 3-Amino-2-pyridones
25天前
已完结
Recent advances in interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitors and PROTACs
1个月前
已完结
Geraniin from the methanol extract of Pilea mongolica suppresses LPS-induced inflammatory responses by inhibiting IRAK4/MAPKs/NF-κB/AP-1 pathway in HaCaT cells
1个月前
已完结
Developing potent anti-inflammatory IRAK4-targeting PROTACs with simplified CRBN ligands
2个月前
已完结
Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis
2个月前
已完结
Anti-inflammatory agents design via the fragment hybrid strategy in the discovery of compound c1 for treating ALI and UC
2个月前
已完结
Cell therapy for neurological disorders
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