Lv4
580 积分 2023-09-01 加入
Chalcones Tethered with Pyridylmethyloxy Tail: Unlocking New Pathways in MDM2-p53 Targeted Cancer Treatment
1个月前
已关闭
2-Pyridylmethyl ether: a readily removable and efficient directing group for amino acidligand accelerated ortho-C–H olefination of phenols
1个月前
已完结
Design, synthesis, and antitumor activity evaluation of potent fourth-generation EGFR inhibitors for treatment of Osimertinib resistant non-small cell lung cancer (NSCLC)
1个月前
已完结
Discovery of a prominent dual-target DDR1/EGFR inhibitor aimed DDR1/EGFR-positive NSCLC
1个月前
已完结
Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies
1个月前
已完结
Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors
1个月前
已完结
Optimization of Potent, Efficacious, Selective and Blood–Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations
1个月前
已完结
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
1个月前
已完结
Novel EGFR inhibitors against resistant L858R/T790M/C797S mutant for intervention of non-small cell lung cancer
1个月前
已完结
The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance
1个月前
已完结
Germanium-Mediated Catalysis via Ge(II)/Ge(III)/Ge(IV) or Ge(II)/Ge(IV) Redox Cycling
4个月前
已采纳
Stress-Induced Anomalous Lithiation Plateau of LiFeyMn1-yPO4 over High-Rate Discharging
4个月前
已采纳
Cold‐Inducible RNA‐Binding Protein Causes Prolonged Immersion‐Induced Hypothermic Acute Lung Injury in a Rat Model Through TREM‐1 and NF‐κB
4个月前
已采纳
Nationwide Survey on Incidence and Management of Recurrent Respiratory Papillomatosis in Japan
4个月前
已采纳
Whole‐Genome Conservation Analysis for the Specific and Accurate Detection of Influenza A and B Viruses and Respiratory Syncytial Virus by Quadruplex RT‐qPCR
4个月前
已采纳
From Good to Better: Comparative Epitope Profiling Facilitates Rational Design of Effective Multi‐Epitope Vaccines Against Viruses
4个月前
已采纳
Clinical study of the pharmacokinetics and pharmacodynamics of Xininurad tablets in patients with renal impairment
4个月前
已采纳
IL‐25 Improves MAFLD by Suppressing the Notch Signalling in Hepatic Macrophages
4个月前
已采纳
Facile Microwave Synthesis of Kilogram‐Scale Electrocatalysts with Nanocarbons Bridged Cobalt Active Sites for Enhanced Oxygen Electrocatalysis (Adv. Energy Mater. 27/2025)
4个月前
已采纳
Early Vascular Response of a Biodegradable Polymer‐Coated Sirolimus‐Eluting Stent in Patients With ST‐Segment Elevation Myocardial Infarction—The OCIMI Study
4个月前
已采纳
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