Lv41
430 积分 2021-07-13 加入
Identification of novel GSPT1 degraders by virtual screening and bioassay
1小时前
已完结
A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
1个月前
已完结
Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders
1个月前
已完结
FGF-based drug discovery: advances and challenges
1个月前
已完结
Finding a needle in the haystack: ADME and pharmacokinetics/pharmacodynamics characterization and optimization toward orally available bifunctional protein degraders
1个月前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
1个月前
已完结
STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases
2个月前
已完结
BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction
2个月前
已完结
The Development of Litifilimab (BIIB 059) for Cutaneous and Systemic Lupus Erythematosus
2个月前
已完结
DB-2304, a Duality Immune Modulating Antibody‒Drug Conjugate (DIMAC) targeting BDCA2, displays strong potency in the suppression of pDC functions
2个月前
已完结