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16 积分 2021-06-07 加入
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
6小时前
已完结
Attachment of Nucleosides and Other Linkers to Solid‐Phase Supports for Oligonucleotide Synthesis
9天前
已完结
A Universal and Recyclable Solid Support for Oligonucleotide Synthesis
9天前
已完结
Impact of Phosphorothioate Chirality on Double‐Stranded siRNAs: A Systematic Evaluation of Stereopure siRNA Designs
26天前
已完结
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates
1个月前
已完结
Synthesis of Phosphorodithioate DNA via Sulfur-Linked, Base-Labile Protecting Groups1
1个月前
已完结
Unlocking biological barriers: nonclinical safety considerations for RNA-based complex biologics
1个月前
已完结
Preclinical evaluation of 68Ga-labeled acetazolamide derivatives as radiotracers targeting carbonic anhydrase IX in clear cell renal cell carcinoma
1个月前
已完结
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
1个月前
已完结
The 9-Fluorenylmethoxycarbonyl (Fmoc) Group for the Protection of Amino Functions of Cytidine, Adenosine, Guanosine and Their 2'-Deoxysugar Derivatives
2个月前
已关闭
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