Lv11
54 积分 2025-12-04 加入
Free Energy Profiles Relating With Conformational Transition of the Switch Domains Induced by G12 Mutations in GTP-Bound KRAS
1小时前
已关闭
ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer
3个月前
已完结
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS(On) Alleles
3个月前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
3个月前
已完结
Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor
4个月前
已完结
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations
5个月前
已完结
Highly Potent, Selective, Biostable, and Cell-Permeable Cyclic d-Peptide for Dual-Targeting Therapy of Lung Cancer
5个月前
已完结
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
5个月前
已完结