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33082 积分 2022-11-11 加入
Flourishing innovation in KRAS targeting: Recent advances in medicinal chemistry strategies and future perspectives
7天前
已完结
KRAS-targeting PROTAC drug passes first clinical test
7天前
已关闭
Novel Carbamate-Based o-aminobenzamide Derivatives as Potent Antigastric Carcinoma Agents via Disrupting NAD+ Salvage Synthesis
14天前
已完结
Structure–Activity Relationships in a Series of Dihydrouracil-JQ1 Conjugates: Discovery of Highly Potent BRD4 Degraders
19天前
已完结
N-Aryl Tetrahydroisoquinolines as Both Reagents and Substrates for Coupling with Alkyl Halides
1个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
1个月前
已完结
Property-based optimisation of PROTACs
1个月前
已完结
In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©
1个月前
已完结
Targeting cancer with small molecule pan-KRAS degraders
1个月前
已完结
Pasteurized Akkermansia muciniphila MucT for weight loss maintenance in people with overweight and obesity: a controlled randomized trial
1个月前
已完结
Temperature effects on the defect states in two-dimensional phononic crystals
5个月前
已采纳
Two-dimensional octagonal phononic crystals for highly dense piezoelectric energy harvesting
5个月前
已采纳
Experimental study on slow flexural waves around the defect modes in a phononic crystal beam using fiber Bragg gratings
5个月前
已采纳
C-reactive protein levels and outcomes after statin therapy
5个月前
已采纳
Mapping sky, tree, and building view factors of street canyons in a high-density urban environment
5个月前
已采纳
Committee
5个月前
已采纳
Mammalian genomes contain active recombinase recognition sites
5个月前
已采纳
Dysregulated Oxygen Metabolism of the Kidney by Uremic Toxins: Review
5个月前
已采纳
EFFICACY OF SIMVASTATIN AND PUMPKIN-SEED OIL IN THE MANAGEMENT OF DIETARY-INDUCED HYPERCHOLESTEROLEMIA
5个月前
已采纳
Hydroperoxide Assay with the Ferric–Xylenol Orange Complex
5个月前
已采纳