Lv3
210 积分 2025-05-10 加入
Discovery of novel rigid STING PROTAC degraders as potential therapeutics for acute kidney injury
11天前
已完结
Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2-Ethynylthiazole-4-carboxamide as Electrophilic Warhead
11天前
已完结
Discovery of novel 2,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridine-7-one derivatives as PDE2 inhibitors with Alzheimer's disease therapeutic potential
11天前
已完结
Design, synthesis, and induction of tumor ferroptosis activity of a novel FSP1 protein degrading agent
11天前
已完结
Discovery of a novel polymyxin adjuvant against multidrug-resistant Gram-negative bacteria through oxidative stress modulation
11天前
已完结
Glibenclamide targets MDH2 to relieve aging phenotypes through metabolism-regulated epigenetic modification
11天前
已完结
X-ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma
11天前
已完结
Discovery and Crystallography Study of Novel Biphenyl Ether and Oxadiazole Thioether (Non-Arylmethylamine)-Based Small-Molecule PD-1/PD-L1 Inhibitors as Immunotherapeutic Agents
11天前
已完结
Hibernating/Awakening Nanomotors Promote Highly Efficient Cryopreservation by Limiting Ice Crystals
11天前
已完结
Engineering microglia as intraoperative optical imaging agent vehicles potentially for fluorescence-guided surgery in gliomas
11天前
已完结