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6 积分 2025-06-25 加入
TNG961 is a selective oral HBS1L molecular glue degrader for the treatment of FOCAD-deleted cancers
4小时前
待确认
PROTAC-based synthetic lethality strategy endogenously activates systemic STING to boost antitumor immunity
7天前
已完结
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein
26天前
已完结
Linker-free PROTACs efficiently induce the degradation of oncoproteins
26天前
已完结
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation
28天前
已完结
Picornavirus VP2 protein suppresses innate immunity through selective autophagic degradation of IKBKE/IKKε
28天前
已完结
Tumor PD-L1 induces β2m ubiquitylation and degradation for cancer cell immune evasion
1个月前
已完结
NEDD4 promotes reactive astrogliosis by enhancing K63-linked ubiquitination and inhibiting chaperone-mediated autophagy degradation of YAP1
1个月前
已完结
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein
1个月前
已完结
TRIM7 negatively regulates CMPK2 suppressing inflammation and apoptosis in renal ischemia-reperfusion injury
1个月前
已完结