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16 积分 2025-06-25 加入
Conformation-Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems
6天前
已完结
Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs
13天前
已完结
A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition
20天前
已完结
Self-Splicing RNA Platform Encodes Twin PROTACs for Dual-E3 Ligase Recruitment and Programmable Protein Degradation
27天前
已完结
A brief overview of the E3 ubiquitin ligase: TRIM7
1个月前
已完结
Discovery of BRD9 PROTAC/IMiD Bifunctional Molecules as Potent Therapeutics for Hematologic Malignancies
1个月前
已完结
Discovery of Effective Dual PROTAC Degraders with Synergistic Antitumor Activity for Overcoming Tamoxifen-Resistant Breast Cancer
1个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
1个月前
已完结
TRIM29-dependent AKR1B10 degradation ameliorates MASH
2个月前
已完结
Selective and Potent First-in-Class CRBN-Dependent Molecular Glue Degraders of WW Domain-Binding Protein 4
2个月前
已完结