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28 积分 2025-06-25 加入
Discovery of Effective Dual PROTAC Degraders with Synergistic Antitumor Activity for Overcoming Tamoxifen-Resistant Breast Cancer
2小时前
待确认
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
7天前
已完结
TRIM29-dependent AKR1B10 degradation ameliorates MASH
13天前
已完结
Selective and Potent First-in-Class CRBN-Dependent Molecular Glue Degraders of WW Domain-Binding Protein 4
20天前
已完结
Structure-Guided Discovery of Novel Dual-Site FEM1B Ligands and Assessment of Their Use in Targeted Protein Degradation
1个月前
已完结
A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition
1个月前
已完结
Engineered Lysosome-Targeted Protein Degradation via Hijacking Macropinocytosis
1个月前
已完结
Self-assembled Nano-PROTACs: bridging chemical design and biological barriers in targeted protein degradation
1个月前
已完结
Photo‐click Proteolysis‐Targeting Chimeras Enable Intracellular Generation of PROTACs for Precise Dual Protein Degradation
2个月前
已完结
Jejunitis following vagotomy in Mann-Williamson dogs
2个月前
已关闭
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