Lv1
40 积分 2025-06-29 加入
Induced proximity-based therapeutic modalities
11小时前
待确认
Review of the impact of fragment-based drug design on PROTAC degrader discovery
10天前
已完结
Development of PolyHis‐Targeting PROTAC Degraders
13天前
已完结
A Novel CSN5 Inhibitor Drives Tumor-Intrinsic PD-L1 Degradation and Exerts Direct Antitumor Efficacy in Triple-Negative Breast Cancer
1个月前
已完结
A Rationally Designed Novel Bifunctional Human TNF-α- and Janus Kinase-Targeted soloMER Drug Conjugate (SDC) with a Neutrophil Elastase Cleavable Linker Delivering Inflammation Site-Specific Release of Payload
3个月前
已完结
Enantioselective Total Synthesis of (+)-Subincanadine F via Organo-SOMO Catalysis
4个月前
已完结
Bifunctional Monothiosquaramide-Catalyzed Enantioselective Addition of Masked Acyl Cyanide to Isatins: Umpolung Strategy for the Total Synthesis of (S)()-Dioxibrassinin and (R)(+)-Spirobrassinin
4个月前
已关闭
First-in-Class Quinoline-Dione-Derived PROTACs: Potent Degraders of Cdc25 Phosphatases for Antitumor Therapy
4个月前
已完结
A Bispecific Peptide–Drug Conjugate Targeting LAG-3 and PD-L1 Harnesses Antitumor Immunity of Macrophages and T Cells
4个月前
已完结