Lv6
3050 积分 2025-06-19 加入
Small molecules that targeting p53 Y220C protein: mechanisms, structures, and clinical advances in anti-tumor therapy
1个月前
已完结
Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator
1个月前
已完结
p53: A tale of complexity and context
1个月前
已完结
Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugs
1个月前
已完结
Design, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs)
1个月前
已完结
Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development
1个月前
已完结
Activating p53Y220C with a mutant-specific small molecule
1个月前
已完结
Extracellular payload release from non-internalizing antibody–drug conjugates: mechanisms and linker technologies
1个月前
已完结
Trial watch: antibody-drug conjugates in cancer therapy
1个月前
已完结
NAPISTAR 1-01: Results of phase 1 dose escalation of monotherapy with TUB-040, a novel NaPi2b-targeting exatecan ADC, in patients (pts) with platinum-resistant ovarian cancer (PROC)
1个月前
已关闭
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