Lv3
248 积分 2024-08-08 加入
An EZH2–SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis
10小时前
待确认
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
10小时前
已完结
Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
2个月前
已完结
A patent review of EZH2 inhibitors from 2017 and beyond
5个月前
已完结
Abstract LB419: HDAC8 over-expression promotes drug resistance and alters chromatin architecture in melanoma cells
5个月前
已完结
Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies
5个月前
已完结
Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade
6个月前
已完结
Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade
6个月前
已完结
Ubiquitin-Specific Protease 7 (USP7) as a Promising Therapeutic Target for Drug Discovery: From Mechanisms to Therapies
6个月前
已完结
Post-genomic illumination of paclitaxel biosynthesis
6个月前
已完结
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