Lv11
20 积分 2022-08-12 加入
Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors
4小时前
求助中
Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors
5个月前
已完结
A combinatorial CRISPR-Cas9 screen identifies ifenprodil as an adjunct to sorafenib for liver cancer treatment
5个月前
已完结
Tasurgratinib in patients with cholangiocarcinoma or gastric cancer: Expansion part of the first-in-human phase I study
5个月前
已完结
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations
6个月前
已完结
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations
6个月前
已完结
Targeted Protein Localization by Covalent 14–3–3 Recruitmen
10个月前
已完结
Structural Analysis of the Macrocyclic Inhibitor BI-4020 Binding to EGFR Kinase
1年前
已完结
FGFR-targeted therapeutics: clinical activity, mechanisms of resistance and new directions
1年前
已完结
Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
1年前
已完结
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