Lv3
280 积分 2024-08-16 加入
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
1天前
待确认
Crystallographic Study Reveals a Cryptic Allosteric Site of FBPase by Sulfonylurea Inhibitors toward T2DM Treatment
10天前
已完结
Discovery of Potent and Brain-Penetrant Inverse Agonists for GPR61, an Orphan G Protein-Coupled Receptor
17天前
已完结
Discovery of AZD9750, an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
1个月前
已完结
Spirocyclopentane as a Novel Scaffold for Potent Ghrelin Receptor Full Agonists
2个月前
已完结
Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective
3个月前
已完结
Overcoming Challenges in the Metabolism of Peptide Therapeutics: Strategies and Case Studies for Clinical Success
3个月前
已完结
Structure-Based Discovery of Quinazolin-2-amine Derivatives as Potent ROR1 Pseudokinase Inhibitors with In Vitro and In Vivo Efficacy against Triple-Negative Breast Cancer
4个月前
已完结
Targeting WRN helicase: Discovery and development of its selective inhibitors
4个月前
已完结
WRN as a Novel Target of Synthetic Lethality: Current Advances and Future Perspectives
4个月前
已完结
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