Lv11
70 积分 2024-08-16 加入
Structural optimization of AR and AR-V7 degraders incorporating silicon-based hydrophobic tags for treatment of castration-resistant prostate cancer
1小时前
待确认
Discovery Processof Enlicitide, a Highly EngineeredMacrocyclic Peptide Therapeutic, through Issue-Driven Fragment-BasedSynthetic Assembly and SAR
18天前
已完结
Discovery of Small Molecule Ligands Targeting Orphan G Protein-Coupled Receptors GPR3, GPR6, and GPR12
2个月前
已完结
Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo
2个月前
已完结
Multicomponent Synthesis of Imidazole-Based Ionizable Lipids for Highly Efficient and Spleen-Selective Messenger RNA Delivery
3个月前
已完结
Copper‐Catalyzed Olefination of 4‐CF3‐Substituted Cyclohexadienones Using Sulfonylmethyl Isocyanides: An Electrostatic Repulsion‐Controlled Regioselectivity Switch Strategy
4个月前
已完结
Alkyl Sulfinates: Formal Nucleophiles for Synthesizing TosMIC Analogs
4个月前
已完结
Facile Preparation of 3,4-Benzocoumarins from 2-Arylbenzoic Acids with NCS and Nai
4个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
4个月前
已完结
Additive-controlled asymmetric iodocyclization enables enantioselective access to both α- and β-nucleosides
4个月前
已完结
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