Lv1
32 积分 2024-01-16 加入
Structure-based engineering of the midnolin-proteasome pathway for targeted protein degradation
16天前
已完结
Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy
1个月前
已完结
Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN
1个月前
已完结
Construction of Small‐Molecule Deubiquitinase‐Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo
1个月前
已完结
Membrane‐Bounded Intracellular E3 Ubiquitin Ligase‐Targeting Chimeras (MembTACs) for Targeted Membrane Protein Degradation
2个月前
已完结
Post-Translational Modifications in Tau and Their Roles in Alzheimer's Pathology
5个月前
已完结
Autophagosome-targeting single-domain antibody clears tau in patient-derived neurons and improves motor function in tauopathy mice
6个月前
已完结
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain
7个月前
已完结
The protective mechanism underlying phenylethanoid glycosides (PHG) actions on synaptic plasticity in rat Alzheimer’s disease model induced by beta amyloid 1-42
7个月前
已完结
AI-driven discovery of dual antiaging and anti-AD therapeutics via PROTAC target deconvolution of a super-enhancer–regulated axis
8个月前
已完结
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