Lv4
470 积分 2024-12-18 加入
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
1个月前
已完结
Human genetic diversity alters off-target outcomes of therapeutic gene editing
2个月前
已完结
Reprogramming CRISPR–Cas enzymes for customized genome editing
6个月前
已完结
Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons
10个月前
已完结
Engineering IscB to develop highly efficient miniature editing tools in mammalian cells and embryos
1年前
已完结
Structural basis for RNA-guided DNA cleavage by IscB-ωRNA and mechanistic comparison with Cas9
1年前
已完结
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
1年前
已完结
Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
1年前
已完结
Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments
1年前
已完结