Lv6
1920 积分 2023-07-12 加入
The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver
18天前
已完结
Simultaneous determination of apatinib and its four major metabolites in human plasma using liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study
23天前
已完结
Determination of Apatinib and its Three Active Metabolites by UPLC–MS/MS in a Phase IV Clinical Trial in NSCLC Patients
23天前
已关闭
A phase I study to investigate the metabolism, excretion, and pharmacokinetics of [14C]fruquintinib, a novel oral selective VEGFR inhibitor, in healthy Chinese male volunteers
24天前
已完结
Effect of Liver Cirrhosis on the Pharmacokinetics, Metabolism, and Tolerability of Daridorexant, A Novel Dual Orexin Receptor Antagonist
3个月前
已完结
Development and validation of an LC-MS/MS method for simultaneous determination of XZP-3287(bireociclib) and its metabolites in human plasma, and its clinical pharmacokinetics application
3个月前
已完结
New drug combination regimen based on pharmacokinetic characteristics-Erdafitinib combined with sertraline or duloxetine
3个月前
已完结
Simultaneous quantitation of befotertinib (D-0316) and its metabolite D-0865 in human plasma by LC-MS/MS method
3个月前
已完结
Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl
3个月前
已完结
Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment
3个月前
已完结