Lv617
2190 积分 2023-07-12 加入
Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK
9天前
已关闭
Characterization of Genetic Variation in CYP3A4 on the Metabolism of Cabozantinib in Vitro
9天前
已完结
Clinical Pharmacokinetics and Pharmacodynamics of Cabozantinib
12天前
已完结
Simultaneous determination of bosutinib and its metabolite in rat plasma by UPLC-MS/MS: Development, validation and application to pharmacokinetic and metabolic stability studies
16天前
已完结
Effects of CYP3A4 variants and drug–drug interactions on the metabolism of fexinidazole
20天前
已完结
Effects of Ketoconazole on the Pharmacokinetics of Ponatinib in Healthy Subjects
20天前
已完结
Evaluation of the effect of multiple doses of rifampin on the pharmacokinetics and safety of ponatinib in healthy subjects
20天前
已完结
Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib
20天前
已完结
The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver
4个月前
已完结
Simultaneous determination of apatinib and its four major metabolites in human plasma using liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study
4个月前
已完结