Lv4
410 积分 2025-05-04 加入
Targeted degradation of activating estrogen receptor α ligand-binding domain mutations in human breast cancer
11小时前
待确认
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
12小时前
已完结
Intercepting the Downstream of the Estrogen Receptor Signaling Pathway: Discovery of a Potent and Efficient SRC-3 PROTAC Degrader for Overcoming Endocrine Resistance Breast Cancer
13小时前
已完结
Structural Optimization of Decoy Oligonucleotide-Based PROTAC That Degrades the Estrogen Receptor
13小时前
已完结
Complete elimination of estrogen receptor α by PROTAC estrogen receptor α degrader ERD-148 in breast cancer cells
13小时前
已完结
Discovery of a Potent RXRγ Degrader WCF-598 for the Treatment of Castration-Resistant Prostate Cancer
17小时前
已完结
Construction of PROTAC Library via Liquid-Phase Synthesis Enabled by a Hydrophobic Tag
17小时前
已完结
Kill Two Birds with One Stone: An Efficient and Potent AR CBS-Targeted Degrader Reverses Breast Cancer Resistance via Concurrent AR Degradation and ERα Transcriptional Suppression
17小时前
已完结
Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer
21小时前
已完结
Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia
21小时前
已完结
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