Lv11
90 积分 2025-04-22 加入
Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells
7小时前
待确认
High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia
1天前
已完结
Selective Covalent Targeting of Anti‐apoptotic BFL‐1 by a Sulfonium‐Tethered Peptide
1天前
已完结
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1
2天前
已完结
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors
10天前
已完结
Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors
10天前
已完结
Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors
27天前
已完结
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models
2个月前
已完结
The RNA Binding Protein HuR: a Promising Drug Target for Anticancer Therapy
2个月前
已完结
Tumor suppressor collateral damage screens reveal mRNA homeostasis protein HBS1L as a novel vulnerability in ch9p21 driven FOCAD deleted cancer
2个月前
已完结
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