Lv2
198 积分 2023-03-14 加入
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design
1个月前
已完结
Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function
1个月前
已完结
Cryo-EM structures of GPR75 reveal an occluded orthosteric pocket challenging conventional drug discovery paradigms for an anti-obesity target
1个月前
已完结
Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations
3个月前
已完结
De novo development of proteolytically resistant therapeutic peptides for oral administration
3个月前
已完结
Next-generation Fc receptor–targeting biologics for autoimmune diseases
3个月前
已完结
Mass Balance and Metabolic Profiling of Avacopan, a Selective C5a Receptor 1 Antagonist, in Healthy Humans
3个月前
已完结
Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist #
5个月前
已完结
Discovery of Reversible Covalent Bruton’s Tyrosine Kinase Inhibitors PRN473 and PRN1008 (Rilzabrutinib)
6个月前
已完结
Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases
6个月前
已完结
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