Lv1
52 积分 2025-06-15 加入
Discovery of R-185 as a Potent and Orally Efficacious GPR52 Agonist with Potential for Treating Schizophrenia and Related Neuropsychiatric Disorders
16天前
已完结
A microbial amino-acid-conjugated bile acid, tryptophan-cholic acid, improves glucose homeostasis via the orphan receptor MRGPRE
22天前
已完结
β-Arrestin Condensates Regulate G Protein-Coupled Receptor Function
1个月前
已完结
A GPCR-G protein-β-arrestin megacomplex enabled by a versatile allosteric modulator
1个月前
已完结
GPCR activation and GRK2 assembly by a biased intracellular agonist
1个月前
已完结
Myeloid Mas drives pyruvate kinase M2-mediated Spi1 lactylation to fuel inflammatory senescence in MASLD
1个月前
已完结
Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM10-TREM2 pathway
1个月前
已完结
Herbacetin as a novel therapeutic agent for pulmonary and renal fibrosis by targeting TGF-βRⅡ for degradation
1个月前
已关闭
A non-enzymatic function of neuraminidase 1 restrains hepatic glucagon response in mice
1个月前
已关闭
Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signaling
2个月前
已完结
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