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760 积分 2025-06-17 加入
Intrahepatic and peripheral immunophenotyping of participants with chronic hepatitis B receiving bepirovirsen in the B-Fine study strongly suggests that bepirovirsen may trigger a humoral response
5小时前
已关闭
Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial
11天前
已完结
Chronic Hepatitis B: Current Understanding and Clinical Implications of Immune Exhaustion
1个月前
已完结
Bepirovirsen immune mechanism of action may potentiate infected hepatocyte killing: Indirect evidence from B-together peripheral longitudinal biomarker analysis
2个月前
已完结
In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides
2个月前
已完结
ALG-000184 (pevifoscorvir sodium) monotherapy in participants with chronic HBV infection: a phase 1, multicentre, randomised, dose escalation trial
2个月前
已关闭
Considerations in the Immunogenicity Assessment Strategy for Oligonucleotide Therapeutics (ONTs)
3个月前
已完结
CMC and regulatory aspects of oligonucleotide therapeutics
3个月前
已完结
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075
4个月前
已完结
External Validation of the GOLDEN Model for Predicting HBsAg Loss in Noncirrhotic Chronic Hepatitis B Patients With Interferon-Alpha-Based Therapy
4个月前
已完结
小儿扁桃体切除术围术期镇痛研究进展
9个月前
已采纳
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